https://blog.hellonico.info/categories/science/ Recent content in Science on NicoLabs Hugo en Tue, 20 Oct 2026 09:50:00 +0900 https://blog.hellonico.info/posts/scc-connectome-deep-brain-stimulation-in-coni/ Tue, 20 Oct 2026 09:50:00 +0900 https://blog.hellonico.info/posts/scc-connectome-deep-brain-stimulation-in-coni/ <p>In neurosurgery, two millimeters is the distance between a life reclaimed and two years of silence.</p> <p>For over two decades, <strong>Subcallosal Cingulate Deep Brain Stimulation (SCC-DBS)</strong>—pioneered by Dr. Helen Mayberg, Dr. Andres Lozano, Dr. Patricio Riva-Posse, Dr. Ki Sueng Choi, and colleagues—has offered a lifeline to patients living with severe, intractable <strong>Treatment-Resistant Depression (TRD)</strong>. By implanting hair-thin four-contact electrodes into <strong>Brodmann Area 25 (BA25)</strong> and delivering continuous 130 Hz electrical pulses, clinicians watched patients who had failed every medication, psychotherapy, and electroconvulsive protocol experience a sudden lifting of visceral dread—and go on to achieve sustained, multi-year remission.</p>